The ACC Research program at TGen, is headed by Michael
Demeure, M.D. and Kimberly Bussey, Ph.D.
The program, analyzes ACC tumors, benign adrenal tumors, and normal
tissue with several genomics technologies. TGen researchers are using the genomics data to identify
mutations in the tumors.
Identifying mutations may help researchers to design new diagnostic tests and therapies to treat ACC.
TGen Headquarters
TGen is a translational
research institute, where researchers are working to identify the genetic
components of common and complex diseases. Translational research means that
these genetic discoveries are quickly “translated” into new diagnostic tests or
therapies to help patients. These
new diagnostic tests and therapies may be tailored to individual patients
depending on their genetic make-up.
TGen scientists work with medical doctors and other scientists in Phoenix and around
the world. In this way, TGen researchers
believe they can make a substantial contribution to the efficiency and
effectiveness of the translational process.
Data produced from samples in this study will have all patient identifying information removed after resulting data is returned to the submitting physician (in the case of prospective submission where the patient has requested results from their tumor sample). De-identified data is published on TGen's web site, which will allow interested scientific investigators access to the data. Results of Repository studies will also be published in a timely fashion. To download the data please follow the instructions below.
To request a username and password call Dr. Bussey at 602-343-8817.
Research Techniques
Used
There are a number of different kinds of research techniques that will be used
to analyze samples in the ACC Repository.
The
researchers will look at the RNA, DNA and protein in the Repository samples to
look for differences in the genetic make-up of people who have ACC and those
who do not. RNA, DNA and protein
are found in every cell in the body.
RNA produces substances in the body (proteins) that allow your cells to
function. Genes are part of
DNA. Genes determine who you are
and what you look like.
If you are a medical professional or you
would like more detailed information about the kinds of research methods that
will be used to analyze the samples, click here:
